Testosterone Replacement Therapy

Testosterone Replace Therapy Methods for Men

Testosterone replacement therapy should be initiated when clinical complaints are accompanied by decreased testosterone levels and confounding factors have been excluded. The aim of therapy should be to re-establish normal sexual functioning, and general mental (eg mood, mental acuity) and physical status (eg muscle mass, muscle strength, virilisation) appropriate to age by the most physiological and risk-free means available.

Two very similar sets of guidelines for the use of testosterone replacement therapy - those of the Endocrine Society (USA) and that of the International Society for The Study of the Aging Male (ISSAM).

The Endocrine Society’s Guidelines were developed and adopted by the First and Second Annual Andropause Consensus Meetings of the Endocrine Society in 2004 and 2005, and were independently reviewed and approved by the Society’s Clinical Affairs Committee.

Testosterone replacement restores serum testosterone to physiological circulating concentrations in men with hypogonadism and reverses the symptoms of androgen deficiency. Thus it is able to produce improvement in libido, increase in bone mineral density and in muscle mass, and produces favourable changes in body composition with reduction in fat mass and increase in lean body mass, improvement in mood, correction of anaemia and improvement in memory performance and cognitive status. Whether testosterone therapy lessens the risk of cardio vascular disease is not established.